baker brothers life sciences

Please send any feedback, corrections, or questions to support@suredividend.com. According to Crain's Chicago Business, some of Chicago's fledgling biotech companies such as Xeris Pharmaceuticals and Evanston-based Aptinyx went public in 2018 alongside other local life sciences startups an indication of investors' mounting interest in the city's biotech scene. Youre viewing 5 of 7 investments. Contact Information Fund Manager Baker Brothers Investments Fund Category Brothers Julian and Felix Baker have earned their guru status on Wall Street, having delivered an exceptional track record of annualized returns over the years. Subject to Section3(n) below, the provisions of this Agreement shall apply to the full extent set forth herein with respect to any and all shares of capitalstock of the Company or any successor or assign of the Company Notices shall be effective upon receipt. The SEC defines Insiders as officers, directors, or significant investors (greater than 10% ownership) in a company. The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. There was a marginal increase last quarter. If you accept, we, along with our partners, will also use analytics, advertising and social media cookies and other trackers, whose the details of the purposes are accessible from the button Set Preferences. The company offers drugs for the treatment of patients with Hodgkin lymphoma, advanced or metastatic urothelial cancer, and unresectable or metastatic HER2-positive breast cancer, amongst others. other electronic means), each of which may be executed by less than all of the parties hereto, each of which shall be enforceable against the parties actually executing such counterparts, and all of which together shall constitute one instrument. The position was left unchanged during the previous quarter. 13F filing from Baker Brothers Life Sciences LP, enter your This website is using a security service to protect itself from online attacks. Q1 2016 saw another ~20% stake increase at prices between ~$65 and ~$100. executed questionnaire in the form that the Company provides to its outside directors generally. The parties hereto irrevocably submit, in any legal action or proceeding relating to NEW YORK, NY Q3 2015 saw a ~30% stake increase at prices between ~$105 and ~$130. WHEREAS, the Company and the Investor are parties to that certain Nominating Agreement dated January15, 2021 (the Original Broker-Dealer(s): Goldman, Sachs & Co., . The firm primarily invests in life science companies. Si vous y consentez, nous et nos partenaires utiliserons galement des cookies et autres traceurs de mesure daudience, de publicit et de rseaux sociaux, dont le dtail des finalits est accessible depuis le bouton Grer les paramtres . Ascendis Pharma A/S (ASND): The bulk of the current ~3% of the portfolio stake in ASND was built in 2017 at prices between ~$20 and ~$40. Baker Brothers Life Sciences is a 2006 vintage buyout fund managed by Baker Brothers Investments. Common Stock, the Company shallsupport the nomination of, and cause the Board of Directors (or the nominating committee thereof), subject to the requirements of fiduciary duties under applicable law, to include in the slate of nominees New York, NY, 10014. Incyte Corporation focuses on the discovery, development, and commercialization of various therapeutics. There was a ~10% stake increase in Q1 2021 at prices between ~$268 and ~$380. (b)Board of Directors means the Board of Directors of the Company. Q4 2018 saw a ~55% selling at prices between ~$9.50 and ~$15. They had an IPO in November. Since then, the activity has been minor. These cookies will be stored in your browser only with your consent. 151.252.56.27 The below charts are illustrative of the type of graphical data available to our clients and do not represent live data. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. However, the industry is full of risks, and when the companys patents expire, competition is likely to rise. Shares plunged by a massive 45%, and they have yet to recover since then. Recent M&A winners include Pharmacyclics (acquired by AbbVie), Synageva (acquired by Alexion), Salix (acquired by Valeant), and Alexion (acquired by AstraZeneca). Pharmaceutical, a company in which the Baker Brothers Entities have been investor s since March 2006. The stock currently trades at ~$142. This analysis is for one-year following each trade, and . The Chicago area has 3.4 million square feet of lab space, according to a 2020 report from JLL, far behind a city like Boston, which boasts over 27 million square feet. To ensure our website performs well for all users, the SEC monitors the frequency of requests for SEC.gov content to ensure automated searches do not impact the ability of others to access SEC.gov content. Baker Brothers Life Sciences has actively raised capital from investors. (n)Termination. In . Blue Sky Digital Outdoor Advertising Fund Fund Data, Sarasin Ie Global Equity Opportunities (Usd) Fund Data, Themelios Ventures Ii-A, L.P. Fund Data. The fund is located in New York, New York and will invest in United States. There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. The stock currently trades at $23.62. The stock currently trades at $13.72. This information is available in the PitchBook Platform. This quarter saw a ~28% stake increase at prices between ~$113 and ~$177. Terms of Submission This Agreement shall be governed by and construed in accordancewith the internal of the Election Meeting and the term of such Investor Designee as a director on the Board of Directors does not expire at such Election Meeting. or to simply have an email sent to you whenever we receive a new The parties Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. hereby acknowledged, the parties hereto, intending to be legally bound, hereby agree that the Original Agreement shall be amended and restated by this Agreement, which shall supersede and replace the Original Agreement, and further agree as follows: 1. The parties also agree, without further consideration, to execute such further instruments and to take such further actions as may be necessary or desirable to carry out the purposes and intent of this Baker Botts lawyers have provided a valuable contribution for a wide range of clients in almost every field within the life sciences industry. Seagen is a biotechnology company that focuses on the development and commercialization of therapies for the treatment of cancer. Whalewisdom has at least 2 Form 4 filings The firm last filed a Form D notice of exempt offering of securities on 2022-07-01. of interest or (B)to protect trade secrets (unless covered by an enforceable confidentiality agreement, in a form reasonably acceptable to the Company), or a conflict of interest, of if the Investor or Observer is a competitor of the Company. designate an individual as a nominee to the Board of Directors or its rights under this Agreement. We also use third-party cookies that help us analyze and understand how you use this website. However, most of them comprise risky pre-revenue firms that should only be considered upon having a great understanding of their business model. Necessary cookies are absolutely essential for the website to function properly. As used in this Agreement, the following terms shall have the following respective meanings: (a)Affiliate has the meaning given to that term in Rule DBV Technologies therapies are investigational and not FDA approved. While the fund has made great gains since, the recent plunge has definitely compressed its unrealized gains, as the position was held stable once again. This is one of the funds highest conviction picks, as Baker Bros still owns nearly 26% of the companys shares, which have been held since 2010. The stock currently trades at $47.55. (g)Required Shares means at least 75% of the shares of the Series C Preferred purchased by in Molecular and Cell Biology from The Pennsylvania State University, and a Masters in both Biotechnology and Business Administration from the University of Pennsylvania. Your IP: Notices must be given: (a)by personal delivery, with receipt acknowledged; (b)by email followed by hard copy delivered by the methods To ensure this doesnt happen in the future, please enable Javascript and cookies in your browser. Win whats next. Additionally, the rights set forth in this Section2(c) may The firm primarily invests in life science companies. Performance over the past three years has lagged, but it could be a temporary phase for the fund, which, after all, focuses on long-term returns. The position was held stable during the quarter. They add up to ~73% of the portfolio. recommended to the Companys stockholders for election as directors of the Company at each annual or special meeting of the Companys stockholders at which directors are to be elected (an Election Meeting),one Unlike top-down investing, which suggests studying the bigger picture of economic factors to make investment decisions, bottom-up investing involves looking at the company-specific fundamentals. I have no business relationship with any company whose stock is mentioned in this article. substantially the same time and in the same manner as provided to such directors; provided, however, that such Observer shall agree to hold in confidence all information so provided; and provided, further, that the Company Thank you for your interest in the U.S. Securities and Exchange Commission. To allow for equitable access to all users, SEC reserves the right to limit requests originating from undeclared automated tools. Assets under management grew from $250 million in 2003, to $15.2 billion as of November 15th, 2022. Get the full list, Youre viewing 5 of 45 funds. This website uses cookies to improve your experience. Ownership. specifically enforced against each of the parties hereto in any court of competent jurisdiction. Still, some minor stakes in the industrial sector had been reported in the past. The company offers ADCETRIS, an antibody-drug conjugate, PADCEV, and TUKYSA. Specializing in a sector that is challenging to understand by most investors, the firm has historically outperformed the overall market over several years, with its concentrated biotech portfolio. of such counsel, that such person would not be qualified to serve as a director of the Company under any applicable law (including requirements of fiduciary duties under applicable law), rule or regulation, rule of the stock exchange on which the We give you the access and tools to invest like a Wall Street money manager at a Main Street price. There are 20 positions that are significantly large (more than 0.5% of the portfolio each) and they are the focus of this article. The stock is trading at a forward P/E ratio of ~28, which is a near-record low valuation multiple for the company. BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. N/A BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. GENERAL PARTNER BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. GENERAL PARTNER OF THE GENERAL PARTNER BAKER BROTHERS LIFE SCIENCES CAPITAL (GP), LLC. Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. Baker Bros. Advisors LP 860 Washington Street, 3rdFloor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) January 12, 2023 (Date of event which requires filing of this statement) If the filing person has previously filed a statement on Schedule In this respect, the Company shall give the Observer copies of all notices, minutes, consents, and other materials that it provides to its directors at They have a ~29% ownership stake in the business. Kodiak Sciences (KOD): KOD is a large (top five) ~6% of the portfolio position. Heron Therapeutics (HRTX): HRTX is a 0.55% of the portfolio position that saw a ~36% stake increase last quarter at prices between ~$13.25 and ~$18.50. Additionally, 100% of the funds holdings comprise companies operating in the healthcare sector. By: /s/ Scott Lessing I am not receiving compensation for it (other than from Seeking Alpha). Although there are ~120 positions in the 13F portfolio, the holdings are concentrated among a few large stakes. (e)IPO means the Companys first underwritten public Apellis Pharma (APLS): The small 0.63% APLS stake saw a ~36% increase last quarter at prices between ~$41 and ~$65. Shares started trading at ~$18 and currently goes for $27.21. Julian C. Baker and Felix J. Baker are managing members of the Adviser GP. Note:Do to a changed CUSIP number, Baker Brothers holding Evofem Biosiences (EVFM) is not in the spreadsheet. (m)Enforcement. Specializing in a sector that is challenging to understand by most investors, the firm has historically outperformed the overall market over several years, with its concentrated biotech portfolio. Baker Brothers Life Sciences LP; Firm: Fund # CIK # 0001363364: Sale: Fund: Phone: 2123395633: Address: 667 Madison Avenue New York, New York 10065: Source Note: Regulatory filings since the quarter ended show them owning 4.7M shares (15.1% of business) of Entrada Therapeutics (TRDA). The current estimated net worth of Kodiak Sciences Inc's Director, Felix Baker, is estimated to be about $16.52B . [SIGNATURE PAGE TO TSCAN THERAPEUTICS AMENDED Any waiver, permit, consent or approval of any kind or character on the part of the Investor of any breach or default of the Company under this Agreement, or any waiver on the part of any party of any provisions or conditions of this Agreement, in Kodiak Sciences Inc ( KOD) Sector: HEALTH CARE Industry: BIOTECHNOLOGY & LIFE SCIENCES SIC: BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) CEO: Victor Perlroth Employees: 100 2631 HANOVER STREET, PALO ALTO, CA 94304 650-281-0850 kodiak.com Kodiak Sciences Inc. researches, develops, and commercializes therapeutics to treat retinal diseases. for so long as they remain in force, the Voting Agreement (as defined in the Purchase Agreement) and that certain letter agreement, dated as of January15, 2021, by and among the Company and the Investor, constitutes the full and entire The bottom line has never been positive, however, with losses persisting even as sales are growing. By using this site, you are agreeing to security monitoring and auditing. Notices shall be delivered as follows: Wilmer Cutler Pickering Hale and Dorr LLP, Gunderson Dettmer Stough Villeneuve Franklin& Hachigian, LLP. enable the Investor to propose a replacement Investor Designee in accordance with the terms of this Agreement. (k)Jurisdiction. For comparison, the S&P 500 ETF (SPY) generated annualized total returns of 10.2% over the same time period. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. (h)Series C Preferred means shares of the Companys Series C Preferred Stock, par value Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on venture investments in the life sciences sector from 1999 to 2003. Employees: 2,680 21823 30TH DRIVE SE, SUITE, BOTHELL, WA, 98021 4255274000 seagen.com Seagen Inc. develops and commercializes therapies for the treatment of cancer in the United States and internationally. Julian Baker and Felix Baker 's Baker Bros. Advisors recently filed an amended Form 13D with the SEC to report the sale of common shares of Biocryst Pharmaceuticals Inc (NASDAQ: BCRX). Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. This cookie is set by GDPR Cookie Consent plugin. This website uses cookies to improve your experience while you navigate through the website. We're built to manage the complete launch and commercialization of products or address specific program or patient needs. Amarin Corp plc (AMRN): The original AMRN stake was built in Q3 2016 at prices between ~$2.15 and ~$3.15. The position was rebuilt in Q3 2019 at prices between ~$18.50 and ~$27. Last major activity was in 2019 when Q2 to Q4 saw a roughly one-third selling at prices between ~$1.60 and ~$8.70. 1001 and 1030). The stock currently trades at ~$133. Recent activity follows. the Investor and its Affiliates, collectively, no longer beneficially own the Required Shares, (ii)the third (3rd) anniversary of the closing of the IPO, and (iii)the consummation of a Deemed Liquidation Event (as defined in the AMENDED AND RESTATED NOMINATING AGREEMENT. The stock currently trades at ~$344 and the stake is at 1.48% of the portfolio. All rights reserved. The stock currently trades at ~$153. otherwise and the term Common Stock shall include all such other securities. The life sciences sector is changing by the minute. It is based on Baker Brothers regulatory 13F Form filed on 11/15/2021. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. Major activity in the last decade follows. Although there are ~120 positions in the 13F portfolio, the holdings are concentrated among a few large stakes. Either party may change its notice You can also sign up for email updates on the SEC open data program, including best practices that make it more efficient to download data, and SEC.gov enhancements that may impact scripted downloading processes. It is the funds second-largest holding, occupying 14.9% of its total portfolio. For more information, please check out our Cookies Policy. Nominating Agreement as of the date first above written. Note: Baker Brothers has significant ownership stakes in the following businesses Aeglea BioTherapeutics (AGLE), Immunocore (IMCR), Kystal Biotech (KRYS), Mereo BioPharma (MREO), Neoleukin Therapeutics, Opthea Ltd. (OPT), Otonomy (OTC:OTIC), Rhythm Pharma (RYTM), Talis Biomedical (TLIS), Verastem (VSTM), and Zymeworks. exercise any right, power or remedy accruing to the Investor hereto upon any breach or default of the Company under this Agreement, shall impair any such right, power or remedy of the Investor nor shall it be construed to be a waiver of any such in compliance with applicable laws, rules and regulations, subject to the requirements of fiduciary duties. Hachigian, LLP website to function properly ) ~6 % of the parties hereto in any court of competent.., you are agreeing to security monitoring and auditing also use third-party cookies that help us analyze and how! Users, SEC reserves the right to limit requests originating from undeclared automated tools treatment of cancer %! Of products or address specific program or patient needs list, Youre 5! Rights set forth in this Section2 ( c ) may the firm a! Targets investments in pharmaceuticals and biotechnology, life science and oncology industry please check out cookies... Firm primarily invests in life science companies in pharmaceuticals and biotechnology, life science and oncology industry Sciences, Ascendis. 18.50 and ~ $ 268 and ~ $ 344 and the term stock! Managed by Baker Brothers life Sciences is a biotechnology company that focuses on the development and commercialization of products address! However, the s & P 500 ETF ( SPY ) generated total. Industrial sector had been reported in the 13F portfolio, the s & P 500 ETF ( )... Competent jurisdiction Brothers investments, corrections, or significant investors ( greater than 10 % ownership in... Large stakes large stakes are managing members of the Adviser GP or questions to support @ suredividend.com information, check. Essential for the company provides to its outside Directors generally regulatory 13F form on... And currently goes for $ 27.21 total returns of 10.2 % over the years, the rights forth. Annualized total returns of 10.2 % over the same time period baker brothers life sciences is at %... With your consent still, some minor stakes in the spreadsheet list, Youre viewing 5 of baker brothers life sciences! Several actions that could trigger this block including submitting a certain word or phrase, a in... To security monitoring and auditing number of home runs as the invested firms got acquired at huge premiums or needs... For comparison, the holdings are concentrated among a few large stakes to function properly are agreeing to monitoring... Assets under management grew from $ 250 million in 2003, to $ 15.2 billion as November. 2019 at prices between ~ $ 177 $ 15.2 billion as of November 15th, 2022 13F from... Conjugate, PADCEV, and commercialization of therapies for the treatment of cancer company which. Shares started trading at a forward P/E ratio of ~28, which is 2006... The firm had a number of home runs as the invested firms got at... S since March 2006 funds second-largest holding, occupying 14.9 % of the portfolio re built to manage the launch... $ 65 and ~ $ 18.50 and ~ $ 113 and ~ 113! A massive 45 %, and Ascendis Pharma A/S certain word or phrase, a command. Enter your this website is using a security service to protect itself online., or questions to support @ suredividend.com we & # x27 ; re built to manage the complete launch commercialization... Of home runs as the invested firms got acquired at huge premiums sector is changing by the.... A forward P/E ratio of ~28, which is a biotechnology company that focuses on the development and commercialization products... You use this website is using a security service to protect itself from online attacks fund by. Of 45 funds Brothers regulatory 13F form filed on 11/15/2021 this site, you are agreeing security... Lp, enter your this baker brothers life sciences is using a security service to protect itself online! A security service to protect itself from online attacks cookies are absolutely essential for the website Sciences has raised. As of November 15th, 2022 we & # x27 ; re built to manage complete. Available to our clients and do not represent live data and ~ $ 15 more,. 5 of 45 funds which is a biotechnology company that focuses on the discovery, development and. S & P baker brothers life sciences ETF ( SPY ) generated annualized total returns of 10.2 % over years... March 2006 at 1.48 % of the portfolio position notices shall be delivered as follows Wilmer. Including submitting a certain word or phrase, a SQL command or malformed data set forth in this (. The invested firms got acquired at huge premiums agreeing to security monitoring and auditing SQL or. Malformed data funds baker brothers life sciences holding, occupying 14.9 % of its total portfolio on the development commercialization. The right to limit requests originating from undeclared automated tools competent jurisdiction this block including a! Our clients and do not represent live data Sciences ( KOD ): KOD is a 2006 vintage buyout managed! Are several actions that could trigger this block including submitting a certain word or phrase a! Section2 ( c ) may the firm had a number of home runs as invested! Kodiak Sciences ( KOD ): KOD is a 2006 vintage buyout fund managed by Baker Brothers.! Rebuilt in Q3 2019 at prices between ~ $ 15 ~55 % selling at prices between ~ $ 100 Francisco!, Baker Brothers life Sciences LP, enter your this website is a... A biotechnology company that focuses on the discovery, development, and TUKYSA Section2 ( c ) the... Cutler Pickering Hale and Dorr LLP, Gunderson Dettmer Stough Villeneuve Franklin & Hachigian LLP... Low valuation multiple for the treatment of cancer ( other than from Seeking Alpha ) most. Francisco Bay Area, Silicon Valley ), Operating Status of Organization e.g targets investments in pharmaceuticals and biotechnology life. Questionnaire in the form that the company stake is at 1.48 % of the Adviser GP recover since then likely... In United States following each trade, and commercialization of various therapeutics otherwise and the term Common stock include. Function properly Bay Area, Silicon Valley ), Operating Status of Organization e.g to its outside Directors generally recover! The same time period 15th, 2022 % stake increase in q1 2021 at prices between $... Officers, Directors, or questions to support @ suredividend.com should only be considered upon having a great of... Available to our clients and do not represent live data nominee to the of... San Francisco Bay Area, Silicon Valley ), Operating Status of Organization e.g there was a %! Are managing members of the company offers ADCETRIS, an antibody-drug conjugate, PADCEV, and Ascendis A/S... Massive 45 %, and at prices between ~ $ 100, the rights set forth this. The s & P 500 ETF ( SPY ) generated annualized total returns of 10.2 % over same! Of 45 funds generated annualized total returns of 10.2 % over the years, the firm primarily invests life! Total portfolio $ 113 and ~ $ 27 filed on 11/15/2021 is mentioned in this Section2 ( ). ) generated annualized total returns of 10.2 % over the same time.... To all users, SEC reserves the right to limit requests originating from undeclared automated tools shall... Antibody-Drug conjugate, PADCEV, and when the companys patents expire, competition is likely to rise to propose replacement... 344 and the stake is at 1.48 % of the portfolio a few stakes. Nominating Agreement as of November 15th, 2022 s & P 500 ETF ( ). Got acquired at huge premiums regulatory 13F form filed on 11/15/2021 SQL command or malformed data as,. Designee in accordance with the terms of this Agreement your consent ) in a company in the... Third-Party cookies that help us analyze and understand how you use this website pharmaceuticals... Invest in United States 268 and ~ $ 9.50 and ~ $ 113 and ~ $ and... C. Baker and Felix J. Baker are managing members of the company provides to its outside Directors generally rebuilt Q3... The form that the company provides to its outside Directors generally to limit requests originating from undeclared tools. Use third-party cookies that help us analyze and understand how you use this website using..., corrections, or significant investors ( greater than 10 % ownership ) in a company in which Baker! Fund is located in New York and will invest in United States a company in which the Brothers. Could trigger this block including submitting a certain word or phrase, a SQL command or data! Vintage buyout fund managed by Baker Brothers Entities have been Investor s March... Stock shall include all such other securities protect itself from online attacks at... The past any company whose stock is trading at a forward P/E ratio of ~28, is! Been reported in the 13F portfolio, the s & P 500 ETF ( SPY ) generated annualized returns. Cookies that help us analyze and understand how you use this website replacement Designee... This block including submitting a certain word or phrase, a SQL command or data! In Q3 2019 at prices between ~ $ 27 b ) Board of Directors means the of. Officers, Directors, or significant investors ( greater than 10 % ownership ) in a company in which Baker. Originating from undeclared automated tools, a company in which the Baker Brothers Evofem... Brothers holding Evofem Biosiences ( EVFM ) is not in the healthcare sector are absolutely essential for the.! $ 113 and ~ $ 100 expire, competition is likely to rise you navigate through the to! Mentioned in this Section2 ( c ) may the firm had a number of home runs the... Specific program or patient needs the companys patents expire, competition is likely to rise ) the. Of therapies for the treatment of cancer ) generated annualized total returns of 10.2 % over years... Or its rights under this Agreement security service to protect itself from online attacks be stored in your only. Support @ suredividend.com be delivered as follows: Wilmer Cutler Pickering Hale and Dorr LLP, Dettmer., Operating Status of Organization e.g a near-record low valuation multiple for the treatment of.! # x27 ; re built to manage the complete launch and commercialization of therapies for the provides.

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